Melanotan II: Rapid Sunless Tanning & Libido Support
Achieve a Natural-Looking Tan, Boost Libido, and Experience Energy Benefits
Melanotan II is a synthetic peptide designed to mimic the effects of α-MSH (alpha-melanocyte-stimulating hormone), a natural compound in the body that influences skin pigmentation, sexual function, and energy balance. Originally developed to reduce the risk of skin cancer by promoting tanning without sun exposure, it has since gained popularity for its unique combination of cosmetic and functional benefits.
In addition to potentially enhancing melanin production for a deep, long-lasting tan, Melanotan II interacts with multiple melanocortin receptors throughout the body. This activity has been shown in some studies to stimulate libido and sexual arousal in both men and women, support mild appetite suppression, and elevate overall energy levels.
Melanotan II acts on multiple melanocortin receptors:
- MC1R: May activate melanin production in melanocytes—responsible for skin pigmentation.
- MC4R: Potentially influences sexual response and appetite regulation in the brain.
- MC3/MC5R: Possibly involved in energy balance, metabolism, and libido.
This broad receptor activity enables Melanotan II to offer aesthetic, sexual, and metabolic benefits in one peptide.
For researchers seeking a peptide which may provide a tanned appearance without harmful UV exposure, alongside the potential for sexual enhancement and improved body composition, Melanotan II offers a compelling, multi-targeted option to consider.
Key Potential Benefits
- Sunless Tanning – Stimulates melanocytes via MC1 receptor activation, offering a customizable tan without sun damage. Fast-acting and UV-responsive for deeper pigmentation.
- Enhanced Libido & Sexual Function – MC4 receptor stimulation has been shown to increase erectile strength, duration, and sexual desire in men; also enhances arousal in women.
- Reduced Appetite & Weight Control – Often leads to appetite suppression and modest weight loss via MC4 activation, aiding in overall metabolic wellness.
- Increased Energy & Mood – Commonly reported side effects include increased energy, reduced fatigue, and mild warming sensation—ideal for active individuals.
Research Sources
- A synthetic analogue of α-MSH used to induce melanogenesis and tanning.
- Dermatology trials noted spontaneous erections and increased sexual desire, leading to development of bremelanotide.
- MC4 receptor engagement leads to appetite suppression and occasional weight loss.
- Users frequently note increased energy, mild facial flushing, and other sympathomimetic effects.
- Reports of serious side effects: rhabdomyolysis, priapism, renal issues, possible melanoma risk from mole darkening, and systemic toxicity.
Technical Information
CAS Number: | 2023788-19-2 |
PubChem CID: | 92432 |
Formula: | C50H69N15O9 |
Synonyms: | Melanotan II, 121062-08-6, Melanotan-II, UPF5CJ93X7, DTXSID90153135 |