Somatropin 50 IU Snap Pen (rhGH)
Ready-to-Mix Dual-Chamber Pen for GH/IGF-1 Axis Research
Our Somatropin Snap Pen contains sequence-identical 191-amino-acid recombinant human growth hormone (rhGH) in a dual-chamber device. The peptide and bacteriostatic diluent are stored separately to help preserve stability; twist to snap the internal seal, gently invert to mix, prime, and dispense. Designed for laboratories and research institutions conducting GH/IGF-1 signaling, metabolism, and tissue-engineering studies.
How It Works (Mechanistic Context for Experiments)
- GHR–JAK2–STAT5 Signaling
Somatropin binds the growth hormone receptor (GHR), activating JAK2 and downstream STAT5 (primarily STAT5b); STAT5 dimers translocate to the nucleus to regulate gene transcription. GH → IGF-1 Axis
GH stimulates hepatic and local tissue production of IGF-1, which circulates bound to IGFBP-3/ALS and mediates many anabolic effects relevant to growth, protein synthesis, and metabolism.Anabolism & Metabolism
In adult physiology, GH shows nitrogen-retaining, protein-synthetic effects (directly and via IGF-1) and interacts with lipid and glucose pathways—key readouts in metabolic and tissue models.
Key Features (for Research Use)
- 191-aa rhGH, sequence-identical to pituitary GH; – ~22 kDa monomeric protein.
- Snap Pen format – on-demand reconstitution, clear graduations for repeatable aliquots, cold-chain fulfillment.
- Quality controls – ≥98% purity (HPLC), low aggregates (SEC-HPLC), endotoxin-tested; COA + SDS supplied per lot.
- Documentation – analytical data, storage/handling guidance, and institutional PO support.
Technical Information
CAS Number: | 12629-01-5 |
Formula: | C990H1529N263O299S7 |


