IGF-1 LR3 1mg Snap Pen

IGF-1 LR3 (Insulin-like Growth Factor-1 Long R3) is a synthetic analogue of naturally occurring IGF-1, modified with a 13-amino-acid extension at the N-terminus and an arginine substitution at position 3. These modifications reduce its binding to IGF-binding proteins (IGFBPs), resulting in a significantly extended half-life of approximately 20–30 hours compared to just 12–15 minutes for standard IGF-1. 

MetaGen's IGF-1 LR3 Snap Pen uses a dual-chamber lyophilised delivery system, keeping the peptide stable in powder form until activation — ensuring maximum potency at the point of use. IGF-1 LR3 works by binding to IGF-1 receptors throughout the body, activating downstream signalling pathways involved in protein synthesis, cellular growth, and glucose uptake. In research models, IGF-1 signalling is associated with hypertrophy (muscle cell growth), satellite-cell activation linked to muscle repair, and fat utilisation as an energy source. This peptide is widely researched in the context of performance recovery, body composition optimisation, and anti-ageing protocols.