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Retatrutide 10mg Snap Pen
Maximize Weight Loss, Glycaemic Control, and Metabolic Health
SKU: SP-RET-10-2
99% PurityTHB 9,800
- Format
- Snap Pen
- Dosage
- 0.1mg per click / Up to 60 clicks per dose.
- Capacity
- 10mg
Not available right now.
Sign in to savePotential benefits
- Dramatic Weight Reduction
- Enhanced Glycemic Control
- Liver Fat & Liver Health Support
- Improved Cardiometabolic Markers
- Favorable Body Composition
- Convenient Weekly Dosing
Retatrutide is an investigational peptide therapy designed to activate three critical metabolic receptors—GLP-1, GIP, and glucagon. This triple agonist approach mimics and amplifies the body’s natural metabolic signals, resulting in profound effects on fat loss, blood sugar regulation, liver health, and inflammation.
What sets Retatrutide apart is its multi-hormone mechanism, which doesn’t just suppress appetite but also increases energy expenditure, reduces visceral and liver fat, and improves overall cardiometabolic function. In clinical trials, Retatrutide has achieved some of the highest weight loss outcomes ever recorded for a non-surgical treatment, while also addressing underlying drivers of metabolic disease.
Retatrutide is a multi-receptor agonist, meaning it activates three hormone pathways simultaneously:
GLP-1 (Glucagon-like Peptide-1): Promotes satiety, slows gastric emptying, and enhances glucose-stimulated insulin secretion.
GIP (Glucose-dependent Insulinotropic Polypeptide): Enhances insulin release in response to meals and synergizes with GLP-1 to improve metabolic response.
Glucagon Receptor: Stimulates fat oxidation, increases energy expenditure, and reduces liver fat stores.
Together, these pathways reshape the body’s energy balance, reduce food intake, burn fat stores, and improve metabolic biomarkers more effectively than single-pathway drugs.
What sets Retatrutide apart is its multi-hormone mechanism, which doesn’t just suppress appetite but also increases energy expenditure, reduces visceral and liver fat, and improves overall cardiometabolic function. In clinical trials, Retatrutide has achieved some of the highest weight loss outcomes ever recorded for a non-surgical treatment, while also addressing underlying drivers of metabolic disease.
Retatrutide is a multi-receptor agonist, meaning it activates three hormone pathways simultaneously:
GLP-1 (Glucagon-like Peptide-1): Promotes satiety, slows gastric emptying, and enhances glucose-stimulated insulin secretion.
GIP (Glucose-dependent Insulinotropic Polypeptide): Enhances insulin release in response to meals and synergizes with GLP-1 to improve metabolic response.
Glucagon Receptor: Stimulates fat oxidation, increases energy expenditure, and reduces liver fat stores.
Together, these pathways reshape the body’s energy balance, reduce food intake, burn fat stores, and improve metabolic biomarkers more effectively than single-pathway drugs.
- Participants in a 48‑week Phase 2 study lost up to 24.2% of initial body weight at higher doses.
- Significant reductions in HbA1c and fasting glucose were observed in adults with obesity ± type 2 diabetes, outperforming monotherapies.
- Over 80% of participants achieved ≥70% reduction in liver fat; >85% resolved steatosis in a MASLD subgroup.
- Notable drops in blood pressure, triglycerides (‑40%+), LDL, and inflammatory biomarkers.
- Retains lean mass while reducing fat mass, based on recent body‑composition data.
- Long half-life (~6 days) allows comfortable once‑weekly subcutaneous injections.
References
- Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
- Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial
- Effects of retatrutide on body composition in people with type 2 diabetes: a substudy of a phase 2, double-blind, parallel-group, placebo-controlled, randomised trial
- What diseases does Retatrutide treat?
- Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial
| Molecular formula | C₂₂₁H₃₄₂N₄₆O₆₈ |
|---|---|
| Molecular weight | 4 Da |
| CAS number | 2381089-83-2 |
| Purity | 99% |
| Storage | Before reconstitution, store 6–50°C, refrigeration is not required. After reconstitution (mixing), keep refrigerated at 2–8°C at all times, use within 6 weeks. Do not freeze. Keep away from direct sunlight and heat. |
Sequence: Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-αMeLeu-Leu-Asp-Lys-Lys(diacid-C20-γGlu-AEEA)-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂
Synonyms: 2381089-83-2, EX-A7826E, GTPL13769
