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Kisspeptin 10mg Snap Pen
A neuropeptide studied for its role in reproductive, metabolic, and cardiovascular pathways via hormone-signalling in the brain.
Snap PenHormonal & Sexual Health
SKU: SP-KISS-10-1
$135
- Format
- Snap Pen
- Dosage
- 0.1 mg per click
- Capacity
- 10mg
Potential benefits
- Pulsatile GnRH-release research (upstream HPG axis)
- Endogenous LH and FSH secretion research
- Natural reproductive hormone-cascade research
- Reproducible micro-dosing via snap-pen
- Puberty-onset and fertility research pathways
Kisspeptin-10 (Kp-10), also known as Metastin (45-54), is the minimum biologically active fragment of the kisspeptin family of neuropeptides encoded by the KISS1 gene. As the master regulator of the hypothalamic-pituitary-gonadal (HPG) axis, kisspeptin acts upstream of GnRH neurons in the hypothalamus, binding to the G protein-coupled receptor KISS1R (GPR54) to trigger pulsatile GnRH release.
This upstream activation drives the downstream secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary, engaging the body's natural hormonal cascade rather than bypassing it in research models. Unlike exogenous gonadotropin analogs, kisspeptin works with the body's existing feedback systems, making it a tool for research into puberty onset, reproductive function, fertility regulation, and HPG-axis dysfunction.
This upstream activation drives the downstream secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary, engaging the body's natural hormonal cascade rather than bypassing it in research models. Unlike exogenous gonadotropin analogs, kisspeptin works with the body's existing feedback systems, making it a tool for research into puberty onset, reproductive function, fertility regulation, and HPG-axis dysfunction.
- Studied for its role in GnRH release and gonadotropin secretion in reproductive function; investigated as a trigger for oocyte maturation in IVF research.
- Investigated in puberty onset, where loss-of-function mutations in kisspeptin signalling are associated with delayed or absent puberty in research.
- Studied for vasoactive effects on the peripheral vasculature and endothelium in research models.
References
| Molecular formula | C63H83N17O14 |
|---|---|
| Molecular weight | 1302.5 Da |
| Storage | Before reconstitution, store 6–50°C, refrigeration is not required. After reconstitution (mixing), keep refrigerated at 2–8°C at all times, use within 6 weeks. Do not freeze. Keep away from direct sunlight and heat. |
Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Synonyms: Kp-10, Metastin (45-54), KISS1 (112-121)
