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PT-141 10mg Easy Pen
Melanocortin-receptor peptide — sexual desire & arousal research
Easy PenHormonal & Sexual Health
SKU: EP-PT1-10-1
99.3% Purity$95
- Format
- Easy Pen
- Dosage
- 0.05mg per click
- Capacity
- 10 mg
Potential benefits
- Sexual-desire research
- Arousal-pathway research (melanocortin)
- Acts without PDE‑5 inhibitors
- Short-Acting, On-Demand Use
- Tolerability research
PT‑141, also known as Bremelanotide, is a melanocortin-receptor peptide studied in sexual-function research, working on the brain’s arousal centers. Unlike traditional treatments that act on blood flow (such as PDE‑5 inhibitors like sildenafil or tadalafil), PT‑141 activates melanocortin receptors in the central nervous system, stimulating desire, motivation, and arousal at the neurological level. This makes it effective in cases where physical function is intact but libido or arousal is lacking, including research relating to sexual desire and arousal.
Initially derived from Melanotan II, PT‑141 was separated out as it was studied for arousal effects without the melanogenesis (tanning) side effects. It is now FDA-approved (as Vyleesi) in clinical research; the molecule (bremelanotide / Vyleesi) continues to be studied in the context of arousal pathways.
PT‑141 mimics natural melanocortin signaling:
Binds to MC3/MC4 receptors in the hypothalamus, key areas for sexual motivation and arousal.
Activates central neuro-endocrine pathways, increasing dopamine and sexual readiness without vascular action.
Studied for quick-onset effects on sexual drive and function, with particular research interest in CNS-based sexual dysfunction.
PT‑141 is typically administered as a subcutaneous injection 30–60 minutes before anticipated intimacy. It works rapidly, with effects lasting up to 6–12 hours in many users, and is often well tolerated with minimal side effects. Its fast action, neural pathway targeting, and effectiveness in individuals unresponsive to conventional medications make it a valuable addition to modern sexual health therapy.
Initially derived from Melanotan II, PT‑141 was separated out as it was studied for arousal effects without the melanogenesis (tanning) side effects. It is now FDA-approved (as Vyleesi) in clinical research; the molecule (bremelanotide / Vyleesi) continues to be studied in the context of arousal pathways.
PT‑141 mimics natural melanocortin signaling:
Binds to MC3/MC4 receptors in the hypothalamus, key areas for sexual motivation and arousal.
Activates central neuro-endocrine pathways, increasing dopamine and sexual readiness without vascular action.
Studied for quick-onset effects on sexual drive and function, with particular research interest in CNS-based sexual dysfunction.
PT‑141 is typically administered as a subcutaneous injection 30–60 minutes before anticipated intimacy. It works rapidly, with effects lasting up to 6–12 hours in many users, and is often well tolerated with minimal side effects. Its fast action, neural pathway targeting, and effectiveness in individuals unresponsive to conventional medications make it a valuable addition to modern sexual health therapy.
- Associated with improved sexual-desire scores in premenopausal women with HSDD on as-needed dosing in clinical research.
- Dose-dependent erectile responses were observed in both healthy individuals and men with mild-to-moderate ED in a double-blind study.
- Acts centrally on MC3/4 receptors, a mechanism studied for relevance to those who don’t respond to PDE‑5 treatments like Viagra or Cialis.
- Typically effective within 30–60 min, making it flexible for clinical and home-use protocols.
- Common side effects include transient nausea, flushing, and headache, generally mild and manageable.
References
- PT-141: a melanocortin agonist for the treatment of sexual dysfunction (PubMed, 2003)
- Co-administration of intranasal PT-141 and sildenafil (ResearchGate, 2003)
- Long-Term Safety and Efficacy of Bremelanotide for HSDD (The Green Journal, 2019)
- Phase I randomized, double-blind safety study of bremelanotide (Sciencedirect, 2017)
| Molecular formula | C50H68N14O10 |
|---|---|
| Molecular weight | 1025.2 Da |
| CAS number | 189691-06-3 |
| Purity | 99.3% |
| Storage | Use within 30 days of first use. Store at 2–8°C / 35–46°F. Protect from sunlight. Do not freeze. |
Sequence: Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Synonyms: Bremelanotide, 189691-06-3, Bremelanotida, 6Y24O4F92S, PT-141 FREE BASE




